Aside from the villagers, who are creepy enough on their own, there are a lot of disturbing enemies you’ll face in the Resident Evil 4 remake. However, no one is tougher to take down than Regenerators. As the name implies, no matter how many bullets you put into these guys, they will just re-grow limb after limb. Furthermore, the classic, “double-tap” to the head trick doesn’t work either, as even this part of their body regenerates. So how do you kill them? Read on to find out!

How to Kill Regenerators in Resident Evil 4

The correct way to kill Regenerators in Resident Evil 4 is with the Biosensor Scope, which you can find on the bottom floor in a briefcase in one of the back rooms of the Incubation Lab. You can equip this scope to either the SR M190, Stingray, or LE 5 SMG. With this scope, when you aim down your sight at a Regenerator, you’ll notice three highlighted areas around its body. These are the parasites in the body that regenerate the limbs and what you need to shoot in order to kill Regenerators. Keep in mind, you must shoot all three to kill properly kill the Regenerator.

While that does give you a way to kill the Regenerators in this section of the game, you won’t have the Biosensor Scope right away, and ammo is always scarce. As a result, you’ll need a backup plan. Your second best option is to shoot the Regenerators’ legs and then stab them in the back. By doing this, there is a chance you’ll stab the parasite. But still, you have to stab all three parasites in the body, which is entirely luck. Meaning, you could end up stabbing the Regenerator a million times and it will still be alive. So this isn’t a very reliable plan.

Aside from that, there are no other ways to kill Regenerators in the Resident Evil 4 remake. The good news, however, is that you don’t have to kill these enemies to progress past this section of the game, though it certainly helps. So, if you’re low on ammo or simply have no other choice, you can use the age-old trick of shooting off their leg and giving them the jukes.

If this guide helped, be sure to check out our other Resident Evil 4 guides below:

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Riley Fonger is a Calgary-based freelance writer. He is currently studying Journalism and Public Relations at Mount Royal University. Riley has been a sports and video game enthusiast since he was a child. If he isn’t writing, he is most likely competing in an FPS game or in a pick-up game with his friends.